Perusing forward on the Comedy Central schedule, I was interested to note that they now have a title posted for episode #316, scheduled to air on December 29th (though for some reason the title isn't listed there; it shows up for the January 1st repeat). The title is "Are you there, God? It's Me, Jesus." The episode description says: "This is the only show that will answer age old questions about who we are and what we're all about." Which, basically, tells us nothing. :)
Interestingly, looking at scheduled repeats, I note that the title of #308 is back to "Two Guys Naked in a Hot Tub" (the "Naked" was missing on the downloads board) and #303 is still listed as "Chef's Mama." Also, note that episode #317 (no title or description yet) is set to debut on January 12th.