After 12 great years, the Simpsons has come to a point where storylines seem almost tired and recycled.
There are too many great characters to let the show's show legacy, so here are my spin-off ideas:
Flanders - The Next Generation. An older Ned tired to deal with the fact that his children have shunned Christian life and go into a life of drugs and debauchery.
Simpsons - The Abraham Years - Grandpa Simpson's younger days are chronicled while Springfield develops into a town.
Moe's - this could be the "Archie Bunker's Place" of the Simpsons.
Patty and Selma - this show would chronicle the struggles of Marge's sisters as they try to quit smoking and overcome the loss of McGyver.
Burns and Smithers - Monty Burns is also featured in his younger days up to the point where Smithers' father dies in a plant accident.