Here's an idea for a spinoff. It probably wouldn't work real well, but here goes. A show with George, his parents, and his brother, that could have constant flashbacks to there childhood, and it would reveal somewhat how he became the way he is now. We've heard about how none of the characters have room to grow like Frazier did and thats why it worked. How about working backwards in George's life and coming to where he is now?
It Might Work