I missed a lot of the shows after season 4. Chandler and Janice were on and off something like four times during that; during which time she got married, divorced, and then reconciled with her ex ("the mattress king")
Then she was back on the show before Monica and Chandler's wedding, when she sort of invited herself and they had to tactfully uninvite her -- and the next time I saw her was when Rachael was in the hospital having Emma, and Janice was having a baby -- I don't recall if this was with a second husband or what.
Whatever happened to that character, was that the end of her appearances in the show?