A few off the top of my head
Not on the list as being too common: The show is an animated sitcom about a family
1. Father who acts retarded most of the time, mom seems of normal intelligence
- Mom who has an unusual voice
- Father is fat, Wife is average weight
- Family consists of an infant, two older children and a dog
5. Father has several friends, one of whom is black, but he doesn't sound black (I hope that isn't a racist thing to say)
- One of father's friends is a single, creepy letch
7. Family lives in a house much bigger than they should be able to afford (maybe this shouldn't be on the list because this is universal on TV. You always see a guy working a job that in reality would pay maybe $55,000/year supporting a stay-at-home spouse, three kids, a new car, wearing designer clothes and living in a five bedroom mansion in the suburbs.)
8. Animated characters have an unusual feature, eyes which consist of large circles with pinpoint pupils
Please feel free to add more