Two guest voices I recognized immediately: Majel Barrett Roddenberry and Wallace Shawn.
Could there be a better choice than Majel as the voice of Stewie's ship? She was cool to do this dialog.
And Wallace Shawn has been a fave of mine since The Princess Bride (Inconceivable!) and was great as Grand Nagus Zek on DS9.
I have to admit that I did not recognize Carol Kane's voice until I saw it in the credits and rewatched her scenes. She didn't do one of her weird voices ala Taxi or Scrooged. Come to think about it, she was in The Princess Bride, too.
BTW, what was the title of this episode?