S06 E04

Stewie Kills Lois

Aired Sunday, November 4, 2007 · 30 min

In the 100th episode, Lois and Peter go on a cruise, leaving Stewie and the family behind. Upset with Lois for leaving him at home, Stewie vows to carry out a diabolical plan. When Brian challenges him to actually do it, Stewie stows away on the ship, finds Lois and - well - the title of the episode says it all.

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